Once-Monthly INVEGA SUSTENNA for Lasting Symptom Control
The #1 long-acting injectable (LAI) with over 13 million prescribed doses*
The #1 long-acting injectable (LAI) with nearly 13 million prescribed doses*
*Data on file.
Treat Schizophrenia With 1 Dose† a Month
INVEGA SUSTENNA is an LAI. This is a type of schizophrenia treatment given by a healthcare provider. What makes LAIs different from a daily pill is that the medication is designed to be slowly released into your system over a specific period of time.
When you know medicine is in your system until your next dose, you can feel more in control of schizophrenia symptoms.
Talk to your healthcare provider to see if INVEGA SUSTENNA is right for you.
†After initial dosing.
INVEGA SUSTENNA put me on track to live a life that I knew I was capable of before my illness. I’ve gotten to a point in my life now where I feel so distant from...experiencing symptoms of schizophrenia. 
– Justin, living with schizophrenia
Individual results may vary.
9 out of 10
adults with
schizophrenia9 out of 10 adultswithschizophrenia
who switched to an LAI said they wish they had started on one sooner.1‡
‡Based on results from a market research survey of 200 adults with schizophrenia. Forty-nine of these patients were current LAI users. In this group, 90% agreed strongly, mostly, or somewhat with the statement above.
1. Brado. Schizophrenia Offer + Acceptance Claims Data Summary. Data on file. Janssen Pharmaceuticals, Inc.; 2023.
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in a clinical study vs 66% on placebo.2||
Talk to your healthcare provider to see if INVEGA SUSTENNA is right for you.
§Only J&J conducted this clinical study.
||The most common adverse events that happened in ≥2% of patients in the double-blind phase of this trial who received INVEGA SUSTENNA were weight increase 7%, nose and throat infection 4%, headache 3%, blood glucose increase 3%, viral stomach infection 2%, and tremor 2%.
2. INVEGA SUSTENNA [Prescribing Information]. Titusville, NJ: Janssen Pharmaceuticals, Inc.
INVEGA SUSTENNA delayed time to relapse when compared to 7 of the most common daily oral schizophrenia medications3
In a 15-month study following adults living with schizophrenia, those taking INVEGA SUSTENNA experienced the following results when compared to those taking 1 of the 7 most common daily schizophrenia medications.
Episode-FreeNearlyEpisode-Free
People who received INVEGA SUSTENNA were relapse-free for an average of 416 days compared to 266 days observed in patients receiving orals.
6-Month-LongerDelay6-Month-Longer Delay
People on INVEGA SUSTENNA had a 30% lower chance of experiencing a relapse compared to those taking 1 of the 7 most common daily schizophrenia medications.
The study included 444 adults living with schizophrenia, with 226 randomly assigned INVEGA SUSTENNA and 218 assigned one of the daily pills. The study wasn’t designed to compare INVEGA SUSTENNA to each individual oral pill.
The most common side effects of INVEGA SUSTENNA seen in this study were:
- Injection site reaction (18.6%)
- Insomnia (16.8%)
- Weight increased (11.9%)
- Akathisia (11.1%)
- Anxiety (10.6%)
Other common side effects seen in previous studies included sleepiness or drowsiness, dizziness, and abnormal muscle movements, including tremor (shaking), shuffling, uncontrolled involuntary movements, or abnormal movements of your eyes.
3.Alphs L, Benson C, Cheshire-Kinney K, et al. Real-world outcomes of paliperidone palmitate compared to daily oral antipsychotic therapy in schizophrenia: a randomized, open-label, review board-blinded 15-month study. J Clin Psychiatry. 2015;76(5):554-561.
A group of 444 adults living with schizophrenia was selected to participate in this 15-month study. These adults were often excluded from trials due to recent histories of arrest and jail time, prior self-reported substance or alcohol abuse, or homelessness.
They were then divided into 2 treatment groups: 1 group took the once-monthly injection INVEGA SUSTENNA, and the other group continued taking 1 of the 7 most common daily pills prescribed by their healthcare professional. The study was not designed to compare INVEGA SUSTENNA to each individual oral pill.
- How was “episode” defined in this study?
- Being admitted to a psychiatric hospital
- Getting arrested or going to jail
- Quitting treatment because of safety or side effects
- Stopping the treatment they were assigned because it wasn’t working
- Adding other treatments because the treatment they were assigned wasn’t working
- Seeking additional help to prevent going back to the hospital
- Suicide
[Taking] INVEGA SUSTENNA... completely changed the dynamic between me and my son. He was able to emotionally connect with me again and tell me he loved me.– Katie, care partner
Talk to your healthcare provider about INVEGA SUSTENNA
